Evaluation of Lipid Profile in the Smokers and Non-Smokers

Evaluation of Lipid Profile in the Smokers and Non-Smokers

  • Vachan Mehta Associate Professor, Department of Medicine, Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat, India
  • Darshak Salat Assistant Professor, Department of Medicine, Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat, India
Keywords: Lipid Profile, smokers, non-smokers, nicotaine


Background: Cigarette smoking leads to increased serum level of total cholesterol, LDL cholesterol, Triglyceride levels and decreased level of anti atherogenic HDL cholesterol. Many studies have shown a dose-dependent relationship between smoking and lipoprotein profile. Hence this study was-taken up to know the lipoprotein pattern in healthy young smokers. Subjects and Methods: Total of hundered healthy smokers and fifty healthy non smokers were included in the study. All the smokers’ subjects were divided in two groups as per the severity of the habit of smoking. Group 1: all those who smoke upto 10 cigarette per day, Group 2: all those who smokemore than 10 cigarette per day. Results: In our study, the mean serum cholesterol of smokers is 205.9 26.1 and that of non-smokers is 165.4 15.2 which is statistically significant Mean HDL-cholesterol is 34.20 4.0 in smokers and 38.40 6.4 in non-smokers, which is statistically significant. Mean LDL-cholesterol is 155.8±29.30 in smokers and 136.70 ±14.45 in nonsmokers which is statistically significant. Mean Triglyceride level in smokers is 163.28±38.7  and in non-smokers it is 116.72±23.3 which is statistically significant. Conclusion: The mean serum lipid values were significantly higher in smokers except HDL-C which were significantly decreased, as compared to non smokers. There is a linear increase in the levels of serum lipids except HDL-C which shows decrease in the levels with the duration and severity of smoking.


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Kanavos P. The rising burden of cancer in the developing world. Ann Oncol. 2006;17:815–823. Available from: https://dx.doi.org/10.1093/annonc/mdl983.

Buttar HS, Li T, Ravi N. Prevention of cardiovascular diseases: Role of exercise, dietary interventions, obesity and smoking cessation. Exp Clin Cardiol. 2005;10:229–229.

Anda RF. Are physicians advising smokers to quit? The patient’s perspective. JAMA-J Am Med Asso. 1987;257(14):1916–1919. Available from: https://dx.doi.org/10.1001/jama.257.14.1916.

Killen JD, Fortmann SP, Schatzberg AF, Arredondo C, Murphy G, Hayward C. Extended cognitive behavior therapy for cigarette smoking cessation. Addiction. 2008;103(8):1381– 1390.

Little HJ. Behavioral mechanisms underlying the link between smoking and drinking. Alcohol Res Health. 2004;24:215–224.

Ch SR, Y ES. The effect of chronic tobacco smoking and chewing on the lipid profile. J Clin Diagn Res. 2013;7(1):31–34. Available from: https://dx.doi.org/10.7860/JCDR/2012/5086.2663.

Granot E, Kohen R. Oxidative stress in childhood—in health and disease states. Clin Nutr. 2004;23(1):3–11. Available from: https://dx.doi.org/10.1016/s0261-5614(03)00097-9.

Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. JAMA. 2004;291(10):1238–1245. Available from: https://dx.doi.org/10.1001/jama.291.10.1238.

O’Toole TE, Conklin DJ, Bhatnagar A. Environmental Risk Factors for Heart Disease. Rev Environ Health. 2008;23(3):167–202. Available from: https://dx.doi.org/10.1515/reveh.2008.23.3.167.

Kilaru S, Frangos SG, Chen AH, Gortler D, Dhadwal AK, Araim O, et al. Nicotine: a review of its role in atherosclerosis

No competing interests declared. J Am Coll Surg. 2001;193(5):538–546. Available from: https://dx.doi.org/10.1016/s1072-7515(01)01059-6.

Hulea SA, Olinescu R, Nitã S, Crocnan D, Kummerow FA. Cigarette smoking causes biochemical changes in blood that are suggestive of oxidative stress: a case-control study. J Environ Pathol Toxicol Oncol. 1995;14(3-4):173–80.

How to Cite
Mehta, V., & Darshak Salat. (2020). Evaluation of Lipid Profile in the Smokers and Non-Smokers. Academia Journal of Medicine, 3(1), 1-3. https://doi.org/10.47008/ajm.2020.3.1.1