@article{Roseline Zohra Ali_Parvez Akhtar_Priyadershini Rangari_2019, title={Evalution of Intubating Conditions and Cardiovascular Effects of Rocuronium, Suxamethanium and Vecuronium}, volume={4}, url={http://aijournals.com/index.php/aan/article/view/1175}, DOI={10.21276/aan.2019.4.2.67}, abstractNote={<p><strong>Background: </strong>Provision of muscle relaxation for endotracheal intubation demands a relatively safer drug than suxamethonium, which can provide good intubating conditions as early as possible with minimal side effects and stable haemodynamic profile.<strong>Objectives:</strong>The present study aimed at evaluating the intubating condition and cardiovascular effects of rocuronium and compares it with suxamethonium and vecuronium. <strong>Subjects and Methods: </strong>The study was conducted on 120 patients divided randomly into three groups of forty each, on the basis of muscle relaxant used for tracheal intubation as Group A with rocuronium, 0.6 mg/kg, Group B with suxamethonium, 1.5 mg/kg and Group C with vecuronium, 0.08 mg/kg.All the patients were premedicated with 0.2 mg glycopyrrolate and anaesthesia was induced by thiopentone sodium 2.5%, 4-5 mg/kg given intravenously then maintained on N20: 02 mixture (66.6% &amp; 33.3%) and intermitted injection of vecuronium. Parameters were observed like onset of apnoea, jaw relaxation, vocal cord position, vocal cord movement, coughing, limb movement cardiovascular response and fasciculations.<strong>Results: </strong>Onset of action in Group A slightly longer than Group B but far shorter than Group C.Fasiculations was absent with both Group A and C but was present with Group C. Intubating condtions were better after Group C. None of the patients developed complication of any type during the procedure. <strong>Conclusion: </strong>It is thus concluded from the above study that rocuronium can very well subsitutesuxamethonium for tracheal intubation when a rapid return to spontaneous respiration is not desired. It thus fills the gap between suxamenthonium and non-depolarizing neuromuscular blocking agents and is a step ahead in search for an ideal neuromuscular blocking drug.</p&gt;}, number={2}, journal={Academia Anesthesiologica International}, author={Roseline Zohra Ali and Parvez Akhtar and Priyadershini Rangari}, year={2019}, month={Dec.}, pages={299-303} }