To Find Optimal Time for Intravenous Fentanyl (1.5µg/Kg) to Attenuate Hemodynamic Response to Laryngoscopy and Intubation

Attenuation of Hemodynamic Response to Laryngoscopy and Intubation

Abstract

Background: Laryngoscopy is often accompanied with a haemodynamic pressor response, which could be hazardous and needs to be suppressed. The aim is to find optimal timing for intravenous low dose Fentanyl (1.5g/Kg) to attenuate hemodynamic response to laryngoscopy and intu- bation. Subjects and Methods: The study was conducted on 100 adult patients for elective surgery under general anaesthesia and endotracheal intubation. The haemodynamic changes (Heart rate and Blood Pressure) were noted after administering intravenous Fentanyl at 3 (Group I) or 5 minutes (Group II). Results: Changes in haemodynamic parameters were more significant in Group I as compared to Group II. Conclusion: Fentanyl when given 5 minutes before intubation effectively attenuates the haemodynamic response to laryngoscopy and endotracheal intubation.